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Cobactan Solution for Injection

Cobactan Solution for Injection
2.5 % w/v suspension for injection » 100ml Vial

  • 2.5 % w/v suspension for injection » 100ml Vial £54.49

Description

For the treatment of bacterial infections in horses and cattle caused by the following Gram positive and Gram negative microorganisms sensitive to cefquinome.

Presentation

Suspension for injection.

Each ml contains:

Cefquinome (as sulfate) 25 mg

Uses

For the treatment of bacterial infections in cattle and pigs caused by the Gram positive and Gram negative microorganisms sensitive to cefquinome:

Cattle

•Respiratory disease caused by Pasteurella multocida and Mannheimia haemolytica.

•Digital dermatitis, infectious bulbar necrosis and acute interdigital necrobacillosis (foul in the foot).

•Acute E. coli mastitis with signs of systemic involvement.

Calves

•E. coli septicaemia in calves.

Pigs

•For the treatment of bacterial infections of the lungs and respiratory tract caused by P. multocida, Haemophilus parasuis, Actinobacillus pleuropneumoniae, Streptococcus suis and other cefquinome-sensitive organisms.

•Mastitis-Metritis-Agalactia Syndrome (MMA) with involvement of E. coli, Staphylococcus ssp., Streptococcus spp. and other cefquinome-sensitive organisms.

Piglets

•Reduction of mortality in cases of meningitis caused by S. suis.

For the treatment of:

•Arthritis caused by Streptococcus spp., E. coli and other cefquinome-sensitive organisms.

•Epidermitis (mild or moderate lesions) caused by Staphylococcus hyicus.

Dosage and administration

See dosage table.

Dosage Table: COBACTAN 2.5%

Species

Indication

Dosage

Frequency

Cattle

Respiratory disease caused by

P. multocida and

M. haemolytica

1 mg cefquinome/kg body weight

(2 ml per 50 kg bw)

Once daily for 3-5 consecutive days

Digital dermatitis, infectious bulbar

necrosis and acute interdigital

necrobacillosis (foul in the foot)

1 mg cefquinome/kg body weight

(2 ml per 50 kg bw)

Once daily for 3-5 consecutive days

Acute E. coli mastitis with signs of systemic involvement

1 mg cefquinome/kg body weight

(2 ml per 50 kg bw)

Once daily for 2 consecutive days

Calves

E. coli septicaemia

2 mg cefquinome/kg body weight

(4 ml per 50 kg bw)

Once daily for 3-5 consecutive days

Pigs

Respiratory disease

2 mg cefquinome/kg body weight

(2 ml per 25 kg bw)

Once daily for 3 consecutive days

MMA

2 mg cefquinome/kg body weight

(2 ml per 25 kg bw)

Once daily for 2 consecutive days

Piglets

Meningitis

Arthritis

Epidermitis

2 mg cefquinome/kg body weight

(2 ml per 25 kg bw)

Once daily for 5 consecutive days

All treatments to be given by intramuscular injection. Studies have indicated the advisability of giving second and subsequent injections at a different injection site. The preferred injection site is in the muscular tissue of the mid-neck region.

To ensure correct dosage, body weight should be determined as accurately as possible to avoid underdosing.

Shake the vial well before using.

The veterinary medicinal product does not contain an antimicrobial preservative. Swab the septum before removing each dose. Use a dry sterile needle and syringe. An appropriately graduated syringe must be used to allow accurate administration of the required dose volume. This is particularly important when injecting small volumes, for example when treating piglets.

The cap may be safely punctured up to 25 times. The 50 ml vial should be used for treating small piglets. When treating groups of animals, use a draw-off needle.

Contra-indications, warnings, etc

Do not use Cobactan 2.5% in animals which are known to be hypersensitive to ß-lactam antibiotics.

Do not administer to animals less than 1.25 kg body weight. Do not use in poultry (including eggs) due to risk of spread of antimicrobial resistance to humans.

Use of the veterinary medicinal product may result in localized tissue reaction. Tissue lesions should resolve 15 days after the last administration of the veterinary medicinal product.

Hypersensitivity reactions to cephalosporins occur rarely.

There is no available information indicating reproductive toxicity in cattle or pigs. In reproduction toxicity studies in laboratory animals cefquinome did not reveal any effect on reproduction or teratogenic potential.

Use only according to the benefit/risk assessment of the responsible veterinary surgeon.

It is known that a cross-sensitivity to cephalosporin exists for bacteria sensitive to the cephalosporin group.

Due to undesirable pharmacodynamic interaction, do not apply cefquinome simultaneously with pharmaceuticals acting bacteriostatically.

Overdoses of 20 mg/kg/day in cattle and 10 mg/kg/day in pigs have been well tolerated.

Cobactan 2.5% selects for resistant strains such as bacteria carrying extended spectrum betalactamases (ESBL) which may constitute a risk to human health if these strains disseminate to humans e.g. via food. For this reason, Cobactan 2.5% should be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly (refers to very acute cases when treatment must be initiated without bacteriological diagnosis), to first line treatment. Official, national and regional antimicrobial policies should be taken into account when the product is used. Increased use, including use of the product deviating from the instructions given in the SPC, may increase the prevalence of such resistance. Whenever possible, Cobactan 2.5% should only be used based on susceptibility testing.

Cobactan 2.5% is intended for treatment of individual animals. Do not use for disease prevention or as a part of herd health programmes. Treatment of groups of animals should be strictly restricted to ongoing disease outbreaks according to the approved conditions of use.

Operator warnings

1.Do not handle this product if you know you are sensitised, or if you have been advised not to work with such preparations.

2.Handle this veterinary medicinal product with great care to avoid exposure, taking all recommended precautions.

3.If you develop symptoms following exposure such as skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms and require urgent medical attention.

4.Cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross sensitivity to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.

Withdrawal periods

Species

Product

Withdrawal Period

Cattle

Meat and offal

5 days

Cattle

Milk

24 hours

Pigs

Meat and offal

3 days

For animal treatment only. Keep out of the sight and reach of children.

Pharmaceutical precautions

Do not store above 25 °C. Protect from light.

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Legal category

POM-V

Packaging Quantities

50 ml and 100 ml multidose bottles.

Not all pack sizes may be marketed.

Further information

Nil.

Marketing authorisation number

Vm 01708/4452.

GTIN (Global Trade Item No)

Cobactan 2.5% 1x100ml:

05032984103946

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:30am - 5:00pm
  • Sat: 9:00am - 1:00pm (Collections only)
  • Email: [email protected]

All prices include VAT where applicable.

Delivery Information

How quickly do you deliver?

Under almost all products on our website is an Estimated dispatch time, check this for a delivery prediction specific to the item you are looking to purchase. These badges are updated live based on the stock levels we have and also those of our suppliers - so are usually very accurate, but cannot be guaranteed. In more general terms, we aim to dispatch all orders within 1 working day of receiving payment (and a prescription if required). If we cannot do so within 3 working days we will contact you by email.

What do you charge for delivery?

For UK delivery, we charge the following:

Order Total Weight Delivery
£0-£28.99 Under 2kg £2.99
2kg+ £4.99
£29-£38.99 Under 2kg Free
2kg+ £4.99
£39+ Under 2kg Free
2kg+ Free

Prices quoted are for delivery to all parts of mainland UK except certain Scottish postcodes (where the price is higher for items sent by courier. Delivery of food abroad (including Channel Islands, N. Ireland and other islands around the UK) is charged at a higher price and free delivery is not available. Temperature controlled products, such as Insulin, are also not always subject to the standard and/or free delivery options.

For full information on our delivery charges, including prices on heavy deliveries to Scotland and abroad, see our delivery information page.

We can deliver most items to all around the world, but prices do vary. The majority of light weight orders (less than 1.5kg) can be delivered for a flat rate of £10. For an accurate estimate of the delivery charge, please put the items you require in your basket and use the "Estimate Delivery" system on the shopping basket page (you only need to enter your country and postal/zip code) for a quick quote. For deliveries to the USA you may need to go to the checkout page and enter your full address to get a quote (as some services need your state in order to quote too). For more information on international deliveries, please see our delivery information page.

Delivery of aerosols

Due to air freight restrictions aerosols cannot ever be sent abroad by Royal Mail. We appreciate your understanding.

Delivery of temperature controlled items

Some products, such as insulin and frozen food, need to be delivered in insulated packaging to prevent them from getting too warm (or too cold) during transit from us to you. Purchasing any of these items in your order will result in a £1.99 charge being added to the total to cover the high cost of the insulated packaging materials. You only pay the £1.99 once per order, regardless of how many temperature controlled items you purchase in that order.

How do I cancel or return an order?

Please call us as soon as possible if you need to amend or cancel an order on 01582 842096. If your order has been processed for dispatch we will be unable to cancel or amend the order. You will however be able to return your product for a full refund*.

To return an item, you must contact us by phone or email to arrange this BEFORE posting any product back to us. We will explain the process at this stage for you.

*For full details on returns, see our terms and conditions page.

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