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Carprodyl is used to treat pain and inflammation in dogs associated with degenerative joint disease (osteoarthritis). It is also useful for injuries to the musculo-skeletal system and for use after operations. It contains the popular drug carprofen, which is one of the most widely used medications of its type in veterinary medicine.
All prices include VAT where applicable.
Clover-shaped scored beige tablet that can be divided into four equal parts.
Target species: Dogs
Reduction of inflammation and pain caused by musculo-skeletal disorders and degenerative joint disease. As a follow-up to parenteral analgesia in the management of post-operative pain.
For oral administration.
4 mg carprofen per kg bodyweight per day.
An initial dose of 4 mg carprofen per kg bodyweight per day given as a single daily dose. The analgesic effect from each dose persists for at least 12 hours.
The daily dose may be reduced, subject to clinical response.
Duration of treatment will be dependent upon the response seen. Long term treatment should be under regular veterinary supervision.
To extend analgesic and anti-inflammatory cover post-operatively parenteral pre-operative treatment with an injectable carprofen may be followed with carprofen tablets at 4 mg/kg/day for 5 days.
Do not exceed the stated dose.
Tablets can be broken as follows: Put the tablet on a flat surface, with its scored side facing the surface (convex face up).
With the tip of forefinger, exert a slight vertical pressure on the middle of the tablet to break it into halves. In order to obtain quarters, then exert a slight pressure on the middle of one half with forefinger.
Each tablet can be quartered for accurate dosing according to the individual body weight of the animal.
50 mg dosage table:
120 mg dosage table:
The chewable tablets are flavoured and are accepted by dogs. The chewable tablets can be administered with or without food.
Do not use in pregnant and lactating bitches.
Do not use in dogs aged less than 4 months in the absence of specific data.
Do not use in cats.
Do not use in dogs, suffering from cardiac, hepatic or renal disease, when there is a possibility of gastrointestinal ulceration or bleeding or where there is evidence of blood dyscrasia.
Do not use in case of hypersensitivity to the active substance, to other NSAID and to any of the excipients.
Adverse reactions (frequency and seriousness)
Typical undesirable effects associated with NSAID, such as vomiting, soft faeces/diarrhoea, faecal occult blood, loss of appetite and lethargy have been reported. These adverse reactions generally occur within the first treatment week and are in most cases transient and disappear following termination of the treatment but in very rare cases may be serious or fatal.
If adverse reactions occur, use of the product should be stopped and the advice of a veterinarian should be sought.
As with other NSAID there is a risk of rare renal or idiosyncratic hepatic adverse events.
Use during pregnancy and lactation
Studies in laboratory species (rat and rabbit) have shown evidence of foetotoxic effects of carprofen at doses close to the therapeutic dose. The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Do not use in pregnant or lactating bitches.
For breeding animals, do not use during reproduction period.
Interaction with other medicinal products and other forms of interaction
Carprofen is highly bound to plasma proteins and compete with other highly bound drugs, which can increase their respective toxic effects.
Do not use this veterinary medicinal drug concurrently with other NSAID or with glucocorticoids.
Concurrent administration of potentially nephrotoxic drugs (e.g. aminogylcoside antibiotics) should be avoided.
Bibliographic data report that carprofen is well tolerated in dogs at twice the recommended dosage for 42 days.
There is no specific antidote to carprofen but general supportive therapy as applied to clinical overdose with NSAIDs should be applied.
Special warnings for each target species
See contraindications and special precautions for use in animals.
Special precautions for use in animals
Use in dogs less than 6 weeks of age, or in aged dogs, may involve additional risk. If such a use cannot be avoided, dogs may require a reduced dosage and careful clinical management.
Avoid use in any dehydrated, hypovolaemic or hypotensive dog, as there is a potential risk of increased renal toxicity.
Concurrent administration of potential nephrotoxic drugs should be avoided.
NSAID can cause inhibition of phagocytosis and hence in the treatment of inflammatory conditions associated with bacterial infection, appropriate concurrent antimicrobial therapy should be instigated.
As with other NSAID, photodermatitis during treatment with carprofen has been observed in laboratory animals and in humans. These skin reactions have never been observed in dogs.
Do not administer other NSAID concurrently or within 24 hours of each other. Some NSAID may be highly bound to plasma proteins and compete with other highly bound drugs, which can lead to toxic effects.
Due to the good palatability of the tablet, they should be stored in a safe place out of the reach of animals. Intake of dose exceeding the recommended number of tablets may lead to severe adverse effects. If this is the case, seek veterinary assistance immediately.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
In case of accidental ingestion, seek medical advice immediately and show the package leaflet to the physician.
Wash hands after handling the product.
Shelf-life after first opening the immediate packaging: 72 hours
50 mg: Cardboard box with 100 tablets containing blisters of 10 tablets / blister.
120 mg: Cardboard box with 120 tablets containing blisters of 6 tablets / blister.
50mg Vm 15052/4094
120 mg Vm 15052/4093
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Below are some recent questions we've received regarding Carprodyl for Dogs, including answers from our team.
I have just read an article in the Daily Mail about Carprodyl. W e do not use this but use Carprieve instead, is this OK?
Both the drugs you name contain carprofen. The danger of this drug comes mainly from giving it to dehydrated animals, or those with kidney or gastro-intestinal symptoms. The dog in the Daily Mail article is fairly typical of the sort of situation where one has to be very careful. My guess is that that vet likes homeopathic treatments, which tends to go with a particular philosophical approach to medicine. Most of the veterinary profession in this country consider homeopathy to be a complete waste of time, which probably means something. I do not know the full details of the case, but this is a Daily Mail article, not a scientific report. A great many vets will read the article and consider it to be an example of veterinary incompetence more than anything else, but I am in no position to judge.
Very, very occasionally a dog which is otherwise perfectly well will show an idiosyncratic reaction to the drug and become seriously ill, but that is immensely rare and will not be the case with your dog because it has been taking the drug anyway. If your dog were to become ill, especially if it showed vomiting or reluctance to eat, you should stop the drug immediately and contact your vet. Even if problems are developing at that time, prompt and correct treatment is usually very effective. If your dog seems well in other respects, but has joint-related mobility problems, carprofen is as safe as you could want from any drug. I bet that I am statistically far more likely to die on my next car journey through a road accident than your dog is likely to suffer suddenly from taking this drug. And I will not be worried about getting into my car. Complete safety does not exist, but these things need to be kept in proportion. A lot of dogs have died after taking this drug, just as a huge number of people have died after taking paracetamol, which is one of the safest drugs there is. Correct use of drugs is the key.
You should use this drug happily while your dog is well in other respects, but be cautious if he shows other illnesses. Carprofen improves the quality of life of millions of older dogs, that is a fact. If I were you I would not be worried, but I would definitely not continue to use the drug in the face of other symptoms of illness. If in doubt, ring your vet.