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  • Capsules for Dogs » Pack of 12 £9.03
  • Liquid for Cats » 60ml Dropper Bottle £13.25
  • Sachets for Horses » 24 x 60g Sachets £53.90

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Calmex is a unique product, formulated to encourage stress relief in dogs, cats and horses. It is can be particularly useful in situations like transport, lifestyle changes, veterinary visits, boarding/kenneling and challenging environments which may make them fearful or anxious.

Calmex contains a unique combination of two amino acids (L-theonine and L-tryptophan) a plant extract (from Piper methysticum) and a range of B vitamins which promotes a more positive mental disposition. Calmex comes in capsules for dogs, liquid for cats and sachets of powder for horses.

Feeding Guidelines

Cat Liquid

1ml per 4.5kg of body weight twice daily, or as recommended by your veterinary surgeon

Dog Capsules

Administer the dose 30-60 minutes before the desired effect is required.

Under 10kg - ½ capsule

10-25kg - 1 capsule

Over 25kg - 2 capsules

Equine Sachets

Body Weight Daily feed amount
Up to 350kg (pony) Half sachet
351 – 600kg (horse) One sachet
Over 601kg (large horse) One and a half sachets

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Questions & Answers for Calmex

Below are some recent questions we've received regarding Calmex, including answers from our team.

Ask Your Own Question

How long do the effects last for

15th Apr 2016
Claire Mattick-Rylands
  • VioVet Customer Since: January 2016
  • From: Devon, United Kingdom

How long does the product last once taken?

John Cousins
  • Veterinary Surgeon

This will normally be for a few hours, but it varies between different animals, with some showing a more obvious effect than others. Very excited animals may not show an obvious response at all, especially when stressed.

Calmex along side adapti

28th Sep 2015
Daniel McCormack
  • VioVet Customer Since: September 2015
  • From: Greater Manchester, United Kingdom

I was wondering can I use the calmex tablets along side adaptil products such as the diffusers and collar ?

John Cousins
  • Veterinary Surgeon

Yes you can safely do this and sometimes combining products with very different modes of action can work well. As with all products like this, you will not really know what the results will be until you try them. It could be worth a try.

Calmex for overgrooming?

16th Aug 2015
Julie Bailey
  • VioVet Customer Since: April 2011
  • From: Leicestershire, United Kingdom

My cat has a problem with stress, he often over grooms and sometimes urine marks inside my house! I currently give him Zylkene which doesn't make much difference to his behaviour, have also tried Feliway, did not work either. Would Calmex be more suitable?

John Cousins
  • Veterinary Surgeon

This is a difficult problem to treat because the causes for the stress vary between cats and some individuals will respond better to one treatment than another, but not all cats will respond to the same product. Generally I find that the Feliway products are the most effective, but you might need to provide a diffuser for each room.

It is worth bearing in mind that the most stressful thing to a cat is usually another cat. It is sometimes possible to try and think of things from your cat's point of view and reduce the amount of stress they feel from neighbour's cats, or indeed your own other cats if you have any. Re-positioning things like food bowls, litter trays and sleeping areas can help sometimes.

Calmex used in welping bitch

6th Apr 2015
VioVet Visitor

My bitch is feeding 7 puppies at the moment, she's gett very stressed when possible buyers come and visit could I use calmex on her??

John Cousins
  • Veterinary Surgeon

It is safe to give Calmex to lactating bitches and it might well help. I would suggest using an Adaptil diffuser in the room too, which is completely safe and certainly helps some dogs a lot.

Calmex and parrots

16th Mar 2015
can calmex be used for parrots

Can calmex be used for parrots with screaming problems?What will be the dosage for birds under 500gr? (African grey cockatoo)

John Cousins
  • Veterinary Surgeon

This can be tried in parrots, but it may or may not make any difference. It is safe enough and you could give a dose of 0.1mls once or twice daily for an African Grey or a similarly sized cockatoo.

Calmex long term?

9th Feb 2015

Can my dog be on calmex long term? and would there any side effects from taking it long term.

John Cousins
  • Veterinary Surgeon

Calmex is perfectly safe and can be used long-term. We would not expect any side effects, though it is possible that the beneficial calming effect would be reduced in time.

Calmex dosage or other product

7th Jan 2015

Hi. I have a border terrier that suffers from intermittent panic attacks and is quite nervous generally. She responds well to calmex during an attack but just wondered if there is another product safe to use daily at a lower dose to keep her more settled day to vet advised to give her half a calmex capsule but the other half is generally wasted as you have to break open the capsule and enevitably it spills out on the floor....making it more expensive.
Alternatively, as we know it works, could I give her the calmex syrup instead and what dose would be a good daily maintenance dose?

John Cousins
  • Veterinary Surgeon

I would keep the Calmex to treat an episode as and when it occurs. For general, every day use you might find that a Thunder Shirt, or Scullcap & Valerian Tablets would help a lot. I would try one or both of those.

Calmex + Feliway

15th Sep 2014
Lauren Richards
  • VioVet Customer Since: June 2014
  • From: Norfolk, United Kingdom

Can this be used alongside a Feliway diffuser?

Danielle Fletcher
  • Category Manager, Own Brand & E-SQP

Yes, Calmex and Feliway can be used together to help your cat to feel reassured and calm. They work in different ways- Calmex ingredients support the nervous system and help with serotonin function-a chemical messenger that to promotes the feeling of well-being. Feliway is a synthetic copy of a cat pheromone which they use to mark objects and territory (including their owners) as familiar. The pheromone given off by Feliway will make them feel more at ease with their surroundings, during stressful events and other situations like introducing a new pet.

Stress/anxiety treatment for dog

18th Feb 2014
Debra Palmer
  • VioVet Customer Since: July 2013
  • From: East Riding of Yorkshire, United Kingdom

My dog suffers from separation anxiety, is fearful of noises, new situations, chases traffic, barks incessantly.
I have already tried rescue remedy, stressless and silent4 - all to no avail.
He is currently on Zylkene once daily and this has helped a little bit but he is still very nervy.
Can he take Calmex in conjunction with the Zylkene?
Can the calmex be taken for long periods?
Does the Calmex have any effect on fertility?

John Cousins
  • Veterinary Surgeon

You can use Clamex for long periods and along with Zylkene and other treatments. However I would say that it sounds like your dog is particularly difficult in this way and most non-prescription treatments will not be powerful enough to have much effect. Often the best combination is Zylkene and Adaptil. Otherwise a low dose of Xanax can work well, but this is prescription-only and you would need it to be prescribed by your vet. Ask your vet about it. Sometimes it works dramatically well for dogs, but some show no response. None of the products would be expected to affect fertility.

Calmex dosage

20th Jul 2013
James Jarrett

I have a 40kg labrador.
We have a long car journey shortly, over a 2 day period.
How frequently can I administer the 2 capsule recommended dose, and can I maintain his level of "sedation" with smaller intermittent doses?
James Jarrett

John Cousins
  • Veterinary Surgeon

The dose can be repeated twice daily for the required duration. It is not intended to cause sedation. Ideally your dog will remain as alert and capable as ever, but will be less anxious and worried. Some dogs appear to respond better than others, with very good results reported sometimes, but less dramatic other times. It probably helps to make yourselves as calm and relaxed as you possibly can too. If you get anxious, your dog will notice that and take it as proof of there being something to be anxious about, and will be worse. (Sometimes dogs and owners seem to get anxious about each other being anxious!)