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Capsules for Dogs » Pack of 12 Capsules for Dogs » Pack of 12 Capsules for Dogs » Pack of 12
Liquid for Cats » 60ml Dropper Bottle Liquid for Cats » 60ml Dropper Bottle Liquid for Cats » 60ml Dropper Bottle
Sachets for Horses » 24 x 60g Sachets Sachets for Horses » 24 x 60g Sachets Sachets for Horses » 24 x 60g Sachets

Images are for illustration purposes only. Packaging may change from time to time and images on our website may or may not be updated.

  • Capsules for Dogs » Pack of 12 £13.00
  • Liquid for Cats » 60ml Dropper Bottle £19.00
  • Sachets for Horses » 24 x 60g Sachets £54.36

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£13.00 to £54.36


Calmex is a unique product, formulated to encourage stress relief in dogs, cats and horses. It is can be particularly useful in situations like transport, lifestyle changes, veterinary visits, boarding/kenneling and challenging environments which may make them fearful or anxious.

Calmex contains a unique combination of two amino acids (L-theonine and L-tryptophan) a plant extract (from Piper methysticum) and a range of B vitamins which promotes a more positive mental disposition. Calmex comes in capsules for dogs, liquid for cats and sachets of powder for horses.

Feeding Guidelines

Cat Liquid

1ml per 4.5kg of body weight twice daily, or as recommended by your veterinary surgeon

Dog Capsules

Administer the dose 30-60 minutes before the desired effect is required.

Under 10kg - ½ capsule

10-25kg - 1 capsule

Over 25kg - 2 capsules

Equine Sachets

Body Weight Daily feed amount
Up to 350kg (pony) Half sachet
351 – 600kg (horse) One sachet
Over 601kg (large horse) One and a half sachets

Need help or advice? Contact us:

  • Landline: 01582 842096
  • Mon - Fri: 8:00am - 6:00pm
  • Sat: 9:00am - 1:00pm
  • Email: [email protected]

All prices include VAT where applicable.

Reviews (75)

Summary of Reviews for Calmex

Overall 4
Ease Of Use
Value For Money
Absence Of Side Effects
58 out of 75 (77%) customers would recommend this product.
5 stars (36 reviews)
4 stars (19 reviews)
3 stars (3 reviews)
2 stars (3 reviews)
1 stars (14 reviews)

Only verified purchasers of this product can leave a review.

55 Very useful
Verified Purchase

By on 22 September 2020

Fireworks, thunder or a change of circumstance can make Tammy very stressy but Calmex is very safe works quickly and clearly makes her settle and feel more comfortable.

Customer recommends this product

45 Calm travel dog
Verified Purchase

By on 31 July 2020

Best product for a calm dog in transit. One capsule 30 mins before you go and no pacing or uncertainty. Makes the drive easy. Much superior to all this ethical natural nonsense!

Customer recommends this product

55 Works wonders!
Verified Purchase

By on 2 December 2019

This really works after about 30 minutes. Not a drug, just vitamins and minerals but worked better on my friends's dog than prescribed nasty sedatives

Customer recommends this product

55 Great product really works
Verified Purchase

By on 2 January 2019

The product is great. It calms Sam down and stops him being so anxious and aggressive. It’s easy to use and lasts quite well.

Customer recommends this product

15 Never again.

By on 1 November 2018

I cant believe im the first to be writing a bad review on these... but Last night ive gave my chowchow these monstrosities!!!

Never again!!!....

One of the worst experiences of my life!! i honestly thought he was going to die! And i think so did he. Falling over everywhere, looked really scared, slow heart rate, uncotrollable bladder, drooling, ears down, panting heavy; completely disoriented...

This wasnt the first time hed had these pills though... the pills were/are in date, and followed the dosage to the correct guidelines. In the end we took him to the vets, and the charged us £30 to tell us to take him to the animal hospital immediately in worsley. We were seen After a 2hour wait, to be told they think its the tablets but its too late as its already in his bloodstream by this point(atleast 3hours later). That cost us £120 and the whole night of making sure he was still with us before even considering going to bed! 5am i stayed up till, just to be sure!! Was easily 12straight hours of panic and fear.

So unless you want to risk all the above;£150 just to be told they cant do anything to help you, 12hours of fear and worry your dog is going to die from all these side effects; dont give these any animal ever!!

go to your vet and ask for a prescription of diazepam(i know right!? Crazy, valium works on dogs apparently, but im not doing it!). Rather a scared dog from a few fireworks than a dead dog from you giving it tablets you dont know are going to work...

honestly never again.

Customer does not recommend this product

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Q & A

Below are some recent questions we've received regarding Calmex, including answers from our team.

26 March 2019 at 8:36pm

Calmex and travel anxiety

Helen Phillips

  • VioVet customer since 2013
  • From: West Sussex, United Kingdom

How soon befor travel should I give our basset calmex ? He has cronic travel anxiety. Is there anything else that we can use along with calmed? A friend suggested adaptil?

  • VioVet Staff

Hi Helen,

You need to administer the dose 30-60 minutes before the desired effect is required.

Hope this helps.

28 June 2017 at 10:57am

Dosage query


I have an 8.6kg shih tzu
What would his dosage be - how many tablets and how often can I give him his tablets
We have a very long car journey 6-7+ hrs

  • VioVet Staff

The dose for your dog would be half a capsule given 30-60 minutes before the start of your journey. The dose can be given twice daily. Supplements like this seem to be very effective for some dogs and not at all for others. If your dog gets particularly anxious travelling it may be worth speaking to your vet about something stronger.

15 April 2016 at 6:17pm

How long do the effects last for

Claire Mattick-Rylands

  • VioVet customer since 2015
  • From: Devon, United Kingdom

How long does the product last once taken?

  • VioVet Staff

This will normally be for a few hours, but it varies between different animals, with some showing a more obvious effect than others. Very excited animals may not show an obvious response at all, especially when stressed.

28 September 2015 at 4:09pm

Calmex along side adapti

Daniel McCormack

  • VioVet customer since 2015
  • From: Greater Manchester, United Kingdom

I was wondering can I use the calmex tablets along side adaptil products such as the diffusers and collar ?

  • VioVet Staff

Yes you can safely do this and sometimes combining products with very different modes of action can work well. As with all products like this, you will not really know what the results will be until you try them. It could be worth a try.

16 August 2015 at 10:09pm

Calmex for overgrooming?

Julie Bailey

  • VioVet customer since 2011
  • From: Leicestershire, United Kingdom

My cat has a problem with stress, he often over grooms and sometimes urine marks inside my house! I currently give him Zylkene which doesn't make much difference to his behaviour, have also tried Feliway, did not work either. Would Calmex be more suitable?

  • VioVet Staff

This is a difficult problem to treat because the causes for the stress vary between cats and some individuals will respond better to one treatment than another, but not all cats will respond to the same product. Generally I find that the Feliway products are the most effective, but you might need to provide a diffuser for each room.

It is worth bearing in mind that the most stressful thing to a cat is usually another cat. It is sometimes possible to try and think of things from your cat's point of view and reduce the amount of stress they feel from neighbour's cats, or indeed your own other cats if you have any. Re-positioning things like food bowls, litter trays and sleeping areas can help sometimes.

6 April 2015 at 8:56pm

Calmex used in welping bitch

VioVet Visitor

My bitch is feeding 7 puppies at the moment, she's gett very stressed when possible buyers come and visit could I use calmex on her??

  • VioVet Staff

It is safe to give Calmex to lactating bitches and it might well help. I would suggest using an Adaptil diffuser in the room too, which is completely safe and certainly helps some dogs a lot.

16 March 2015 at 3:54pm

Calmex and parrots

can calmex be used for parrots

Can calmex be used for parrots with screaming problems?What will be the dosage for birds under 500gr? (African grey cockatoo)

  • VioVet Staff

This can be tried in parrots, but it may or may not make any difference. It is safe enough and you could give a dose of 0.1mls once or twice daily for an African Grey or a similarly sized cockatoo.

9 February 2015 at 3:00pm

Calmex long term?


Can my dog be on calmex long term? and would there any side effects from taking it long term.

  • VioVet Staff

Calmex is perfectly safe and can be used long-term. We would not expect any side effects, though it is possible that the beneficial calming effect would be reduced in time.

7 January 2015 at 8:24pm

Calmex dosage or other product


Hi. I have a border terrier that suffers from intermittent panic attacks and is quite nervous generally. She responds well to calmex during an attack but just wondered if there is another product safe to use daily at a lower dose to keep her more settled day to vet advised to give her half a calmex capsule but the other half is generally wasted as you have to break open the capsule and enevitably it spills out on the floor....making it more expensive.
Alternatively, as we know it works, could I give her the calmex syrup instead and what dose would be a good daily maintenance dose?

  • VioVet Staff

I would keep the Calmex to treat an episode as and when it occurs. For general, every day use you might find that a Thunder Shirt or Scullcap & Valerian Tablets would help a lot. I would try one or both of those.

15 September 2014 at 5:49pm

Calmex + Feliway

Lauren Richards

  • VioVet customer since 2014
  • From: Norfolk, United Kingdom

Can this be used alongside a Feliway diffuser?

  • VioVet Staff

Yes, Calmex and Feliway can be used together to help your cat to feel reassured and calm. They work in different ways- Calmex ingredients support the nervous system and help with serotonin function-a chemical messenger that to promotes the feeling of well-being. Feliway is a synthetic copy of a cat pheromone which they use to mark objects and territory (including their owners) as familiar. The pheromone given off by Feliway will make them feel more at ease with their surroundings, during stressful events and other situations like introducing a new pet.

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