Rimadyl

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Rimadyl is a medication used to control pain in dogs. It is administered just once a day for relief from pain and inflammation and is often used when the pet has undergone surgery or is suffering from conditions such as arthritis. Rimadyl for dogs works by controlling the hormones and enzymes that can lead to pain and inflammation. The active ingredient, carprofen, is effective for relief of pain and inflammation. It is used for degenerative joint disease (osteoarthritis) and other situations where these properties are helpful, such as following an injury or after surgical operations.

Rimadyl for dogs comes in a number of formulas. The regular Rimadyl tablets are small, white tablets, intended to be placed directly into the dog's mouth. The chewable palatable tablets make administration easy for dog owners and the tablets are flavoured to make them more acceptable to the pet.

Rimadyl granules can be used in horses and ponies to treat pain and inflammation which occurs as a result of musculo-skeletal injury, or following surgery. The granules can be given for up to 9 days, and are normally added to food as a follow-up treatment for an intravenous injection given by the vet.

It may be that some dogs experience a reaction or intolerance while on Rimadyl. Signs to watch out for include a change in appetite, diarrhoea or sickness. If your pet shows any symptoms while taking Rimadyl for dogs then a vet should be consulted immediately. Pregnant or nursing dogs should not be given Rimadyl and your vet should be aware of any other medications to rule out the possibility of drug interaction.

Rimadyl is a prescription-only medication and in order to purchase pet medicine online from Viovet, it is necessary to obtain a written pet prescription from a vet. The prescription must be sent with the order before the medication can be supplied.

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Rimadyl Palatable Tablets 20 mg, 50 mg & 100 mg

Presentation

Rimadyl Palatable Tablets for dogs are square light brown tablets scored down the middle containing as active ingredient either 20 mg, 50 mg or 100 mg carprofen.

Uses

For analgesia and reduction of chronic inflammation, for example in degenerative joint disease of the dog. Rimadyl Palatable Tablets can also be used in the management of post-operative pain in dogs.

Dosage and administration

For oral administration. The tablets are palatable and are willingly consumed by most dogs when offered.

An initial dose of 2 to 4 mg carprofen/kg bodyweight/day is recommended to be given as a single dose or in two equally divided doses. Subject to clinical response the dose may be reduced after 7 days to 2 mg carprofen/kg bodyweight/day given as a single daily dose. To extend analgesic and anti-inflammatory cover post operatively, parenteral therapy with Rimadyl Small Animal Injection may be followed with Rimadyl Palatable Tablets at 4mg/kg/day for up to 5 days.

Duration of treatment will be dependent upon the response seen. Long term treatment should be under regular veterinary supervision.

Contra-indications, warnings, etc

The elimination time of NSAIDs, including carprofen, in the cat is longer than in the dog and the therapeutic index is narrower. In the absence of specific data the use of Rimadyl Palatable Tablets in the cat is contra-indicated.

Do not exceed the stated dose.

Do not administer other NSAIDs concurrently or within 24 hours of each other. Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound drugs, which can lead to toxic effects.

Do not use in dogs suffering from cardiac, hepatic or renal disease, where there is a possibility of gastro-intestinal ulceration or bleeding, or where there is evidence of a blood dyscrasia or hypersensitivity to the product. As with other NSAIDs there is a risk of rare renal or idiosyncratic hepatic adverse events.

Use in dogs less than 6 weeks of age, or in aged dogs, may involve additional risk. If such use cannot be avoided, such dogs may require a reduced dosage and careful clinical management.

Avoid use in any dehydrated, hypovolaemic or hypotensive dog, as there is a potential risk of increased renal toxicity.

Concurrent administration of potential nephrotoxic drugs should be avoided.

In the absence of any specific studies in pregnant bitches, such use is not indicated.

NSAIDs can cause inhibition of phagocytosis and hence in the treatment of inflammatory conditions associated with bacterial infection, appropriate concurrent antimicrobial therapy should be instigated.

For animal treatment only.

Due to the palatable nature of the tablets, store in a secure location. Severe adverse reaction may occur if large quantities are ingested. If you suspect your dog has consumed Rimadyl Palatable Tablets above the labelled dose, please contact your veterinarian.

There is no specific antidote for carprofen overdosage but general supportive therapy, as applied to clinical overdosage with NSAIDs should be applied.

In the event of accidental ingestion of the tablets, seek medical advice and show the doctor what has been taken.

Wash hands after handling the product.

Pharmaceutical precautions

Do not store above 25°C. Store in a dry place. Protect from light. Keep out of reach of children.

Any unused product or waste materials should be disposed of in accordance with national requirements.

Legal category

POM-V

Packaging Quantities

Containers of 14, 30 or 100 tablets x 20 mg, 14, 30 or 100 tablets x 50 mg, 14, 30 or 100 tablets x 100 mg

Further information

Experimental and clinical evidence suggests that for carprofen in the dog gastro-intestinal tract ulceration is rare, and only occurs at dosages well above the therapeutic dose.

Following repeated therapeutic dosing for 8 weeks, carprofen has been shown to have no detrimental effect on chronically arthritic canine cartilage in a model of canine osteoarthritis.

In addition, therapeutic concentrations of carprofen have been demonstrated (in vitro) to increase proteoglycan synthesis in chondrocytes from canine arthritic cartilage.

Stimulation of proteoglycan synthesis will narrow the difference between the rate of degeneration and regeneration of cartilage matrix resulting in a slowing of the progression of cartilage loss.

Marketing authorisation numbers

20 mg

Vm 00057/4215

50 mg

Vm 00057/4216

100 mg

Vm 00057/4217

GTIN (Global Trade Item No)

14 x 20 mg:

05013457079098

30 x 20 mg:

05013457079104

100 x 20 mg:

05013457079111

14 x 50 mg:

05013457079128

30 x 50 mg:

05013457079135

100 x 50 mg:

05013457079142

14 x 100 mg:

05013457079159

30 x 100 mg:

05013457079166

100 x 100 mg:

05013457079173

Rimadyl Tablets 20 mg & 50 mg

Presentation

Rimadyl Tablets are round white tablets scored down the middle containing as active ingredient either 20 mg or 50 mg carprofen.

Uses

For analgesia and reduction of chronic inflammation, for example in degenerative joint disease of the dog. Rimadyl tablets can also be used in the management of post-operative pain in dogs.

Dosage and administration

For oral administration.

An initial dose of 2 to 4 mg carprofen/kg bodyweight/day is recommended to be given as a single dose or in two equally divided doses. Subject to clinical response the dose may be reduced after 7 days to 2 mg carprofen/kg bodyweight/day given as a single daily dose. To extend analgesic and anti-inflammatory cover post operatively, parenteral therapy with Rimadyl Injection may be followed with Rimadyl tablets at 4 mg/kg/day for up to 5 days.

Duration of treatment will be dependent upon the response seen. Long term treatment should be under regular veterinary supervision.

Contra-indications, warnings, etc

The elimination time of NSAIDs, including carprofen, in the cat is longer than in the dog and the therapeutic index is narrower. In the absence of specific data the use of Rimadyl Tablets in the cat is contra-indicated.

Do not exceed the stated dose.

Do not administer other NSAIDs concurrently or within 24 hours of each other. Do not administer in conjunction with glucocorticoids.

Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound drugs, which can lead to toxic effects.

Do not use in dogs suffering from cardiac, hepatic or renal disease, where there is a possibility of gastro-intestinal ulceration or bleeding, or where there is evidence of a blood dyscrasia or hypersensitivity to the product. As with other NSAIDs there is a risk of rare renal or idiosyncratic hepatic adverse events.

Use in dogs less than 6 weeks of age, or in aged animals, may involve additional risk. If such use cannot be avoided, such dogs may require a reduced dosage and careful clinical management.

Avoid use in any dehydrated, hypovolaemic or hypotensive dog, as there is a potential risk of increased renal toxicity.

Concurrent administration of potential nephrotoxic drugs should be avoided.

In the absence of any specific studies in pregnant target bitches, such use is not indicated.

NSAIDs can cause inhibition of phagocytosis and hence in the treatment of inflammatory conditions associated with bacterial infection, appropriate concurrent antimicrobial therapy should be instigated.

There is no specific antidote for carprofen overdosage but general supportive therapy, as applied to clinical overdosage with NSAIDs should be applied.

For animal treatment only.

In the event of accidental ingestion of the tablets, seek medical advice and show the doctor what has been taken.

Wash hands after handling the product.

Pharmaceutical precautions

Store in a dry place. Protect from light. Keep out of reach of children.

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Legal category

POM-V

Packaging Quantities

Containers of 100 × 20 mg, 100 × 50 mg and 500 × 50 mg tablets.

Further information

Experimental and clinical evidence suggests that for carprofen in the dog gastro-intestinal tract ulceration is rare, and only occurs at dosages well above the therapeutic dose.

Marketing authorisation numbers

20 mg

Vm 00057/4190

50 mg

Vm 00057/4191

GTIN (Global Trade Item No)

100 x 20 mg:

05013457078350

100 x 50 mg:

05013457078367

500 x 50 mg:

05013457078374

Need help or advice? Contact us:

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Questions & Answers for Rimadyl

Below are some recent questions we've received regarding Rimadyl, including answers from our team.

Alternative to Rimadyl 16th Dec 2013

Rimadyl upsets my older GSD. What else can I use?

  • Website Content Developer at VioVet

Given the age and breed of your dog, I suspect she is going to have some soreness from her hips whatever you do. However, it is possible to help her. First I would try and get her to lose a little weight if she is at all over-weight. This makes a huge difference to dogs with mobility problems. Reduce her food level slightly, or try a diet type of food. Secondly I would encourage her to get up gently and move about a bit, lots of times in the day. Not very much is needed at a time, but regular movement keeps the hips from getting stiff.

I would recommend you give her two medications as well. One would be a nutriceutical such as Seraquin or Cosequin. They do not cause any trouble for the kidneys and are usually easy to digest. The other thing would be a different non-steroidal anti-inflammatory drug. If Rimadyl upsets her, then you might well find that Previcox or Onsior is safe to use. They are designed to be kinder on the gut lining and kidneys than Rimadyl. They need a prescription though from your vet. You can however just buy the Seraquin or Cosequin from our website.

Answer written by John Cousins BVSc MRCVS