Yellow-orange transparent gel for oral administration. Each ml contains acepromazine (as maleate) 35.0 mg and methyl-4-hydroxybenzoate 0.65 mg and propyl-4-hydroxybenzoate 0.35 mg as preservatives.

For sedation of horses

For oral administration. The oral doser contains 10 ml and has graduations at 1 ml intervals.

Moderate sedation:	0.15 mg Acepromazine/kg bodyweight

Sedalin Gel
Body wt.	100 kg	200 kg	300 kg	400 kg	450 kg	500 kg	600 kg
Dose (ml)	½	1	1 ½	1 ½	2	2 ½	2 ½

The dosage information is provided as a guideline. The dose may be varied to administer between ½ and 1 ½ times the above recommendation according to the level of sedation required, i.e. for mild sedation, administer half the recommended dose and for deeper sedation, administer 1 ½ times the recommended dose.
The syringe is brought into the animal’s mouth and the suitable dose is pumped into the cheek pouch. The palatable Gel can also be mixed with food.

Not for use in animals in shock or post traumatically, or with existing severe emotional excitation or epilepsy.
Do not use in cases of post traumatic hypovolemia.
Acepromazine should not be used in pregnant or lactating mares.
Since acepromazine decreases sympathetic nervous system tone, a transient drop in blood pressure may occur after its administration, and inhibition of temperature regulation.
The following reversible changes are possible in the haemogram: Transient decrease in the erythrocyte count and haemoglobin concentration as well as in thrombocyte and leukocyte counts.
Because it increases prolactin secretion, the administration of acepromazine may lead to disturbances in fertility.
In stallions the lowest dose range is indicated to minimize prolapse of the penis. Penile prolapse may occur due to the relaxation of the retractor penis muscles. Retraction of the penis should be visible within two to three hours. If this does not take place, it is advised to contact a veterinary surgeon. Lack of retraction is of particular concern in breeding stallions. Acepromazine has caused paraphimosis sometimes in a sequel to priapism.
Acepromazine potentiates the action of centrally depressant drugs. The simultaneous use of organic phosphate esters increases the toxicity of acepromazine. Since acepromazine decreases sympathetic nervous system tone, it should not be given at the same time as blood pressure reducing drugs.
Sedation lasts for approximately six hours, although the actual time and depth of sedation are very dependent on the status of the individual animal. Increasing the dosage results in prolonged action and side effects but no greater sedation.
Overdosage results in an earlier onset of the sedative symptoms and in a prolonged effect.
Toxic effects are: ataxia, hypotensia, hypothermia, extrapyramidal effects.
Noradrenaline can be used to counteract the cardiovascular effects. Methylamphetamine has been recommended for the treatment of aberrant reactions in horses.
Withdrawal period
Not for use in animals for human consumption
Operator warning
In the case of accidental ingestion contact a physician showing the pack insert or product label to the physician. Wash hands immediately after use. In the event of leakage or accidental spillage, wash affected areas immediately. Overdosage results in an earlier onset of the sedative symptoms and in a prolonged effect.

POM-V (previously POM)

10 ml polyethylene syringe fitted with polyethylene overcap.

Acepromazine is a phenothiazine derivate. This group of molecules belongs to the neuroleptica: they depress the central nervous system and exert associated effects on the autonomic system. These effects are due to their interference with different neurotransmitter receptors (dopaminergic, adrenergic) and to their interference with hypothalamic performance.
The desired effects observed after treatment with acepromazine include a general tranquillizing effect, anti-emetic effect and a slight antihistaminic effect. There is no analgesic action. The neuroleptical effects are variable between individual animals.
Acepromazine is partly absorbed from the gastrointestinal tract. It binds extremely well to plasma proteins and is extensively distributed over the body tissues. Plasma levels are usually low. Acepromazine is highly metabolized and excreted in urine. The sedative activity starts within 15-30 minutes and lasts up to 6-7 hours.