Below is the product datasheet. This has been provided by the manufacturer and should always be provided with the medication. Introduction 
Company name: Pfizer Limited
Address: Ramsgate Road
Sandwich
Kent CT13 9NJ
Telephone: 0845 300 8034 (Out of hours: 01304 616161)
Fax: 01737 332521
Email: UKVetLine@pfizer.com
Website: www.pfizerah.co.uk
Presentation
White, free-flowing granules containing carprofen 8.75% w/w.
Uses
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. In horses and ponies it is indicated for analgesic and anti-inflammatory action in musculo-skeletal disorders and after surgery.
Dosage and administration
The recommended dosage is 0.7 mg carprofen per kg bodyweight. In all cases it is recommended that this be provided initially by an intravenous injection of carprofen, followed by once daily oral administration of the granules for up to 4 or 9 days according to clinical response. One sachet of Rimadyl Granules treats 300 kg bodyweight. For animals below 150 kg the use of half a sachet is recommended.
Rimadyl Granules should be administered with a little feed, mixed in to ensure the full dose is eaten.
Contra-indications, warnings, etc
For oral administration only.
For specific information about the time which must elapse between treatment and competition, veterinary surgeons are advised to consult the authority responsible for the competition in question (e.g. the Jockey Club in the case of racing in the UK).
Do not exceed the stated dose or the duration of treatment.
Do not administer other NSAIDs concurrently or within 24 hours of each other.
Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound drugs which can lead to toxic effects.
Do not use in animals suffering from cardiac, hepatic, renal disease where there is a possibility of gastro-intestinal ulceration or bleeding or where there is evidence of a blood dyscrasia or hypersensitivity to the product.
Use in any animal less than 6 weeks of age, or in aged animals, may involve additional risk. If such a use cannot be avoided animals may require a reduced dosage and careful clinical management.
Avoid use in any dehydrated, hypovolaemic or hypotensive animal, as there is a potential risk of increased renal toxicity. Concurrent administration of potential nephrotoxic drugs should be avoided.
NSAIDs can cause inhibition of phagocytosis and hence in the treatment of inflammatory conditions associated with bacterial infection, appropriate concurrent antimicrobial therapy should be instigated.
In the absence of any specific studies in pregnant target animals, such use is not indicated.
There is no specific antidote for carprofen overdosage but general supportive therapy as applied to clinical overdosage with NSAIDs should be applied.
For animal treatment only.
Withdrawal period
Not for use in horses intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse must have been declared as not intended for human consumption under national horse passport legislation.
Operator warnings
Wash hands after use. Avoid inhalation of the product.
Pharmaceutical precautions
Do not store above 25°C. Protect from light. Store in a dry place.
Any unused, opened sachets should be discarded at the end of a course of treatment.
Any unused product or waste material should be disposed of in accordance with national requirements.
Keep out of reach of children.
Legal category
POM-V
Packaging Quantities
Cartons containing 20 sachets. Each sachet contains 2.4 g Rimadyl Granules (210 mg carprofen).
Further information
Both carprofen and warfarin may be bound to plasma proteins. Limited evidence indicates that binding is at different sites thus enabling concurrent use, but the clinical situation must be monitored carefully.
Marketing authorisation number
Vm 00057/4192.
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