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Clinacin Tablets

Clinacin tablets contain the well proven veterinary antibiotic clindamycin. This antibiotic is used by many vets to treat infected wounds, abscesses, infections over the surface of the skin, and infections in the mouth and affecting the teeth. It is often used prophylactically prior to dental or oral surgery to provide antibiotic cover where this is thought to be needed. Clindamycin penetrates into bone effectively, so it is also used for some cases of osteomyelitis. The tablets are given either once or twice daily, according to the type of infection being treated.

Description

Presentation

25mg - White round tablets with a breakline on one side. Each tablet contains 25 mg clindamycin (as hydrochloride).

75mg - White round tablets with a breakline on one side. Each tablet contains 75mg clindamycin (as hydrochloride)

150mg - White oblong tablets with a breakline on one side. Each tablets contains 150mg clindamycin (as hydrochloride)

300mg - White round tablets with a breakline on one side. Each tablets contains 300mg clindamycin (as hydrochloride)

Uses

Clinacin tablets are indicated for the treatment of infected wounds, abscesses, superficial pyoderma and oral cavity/dental infections caused by or associated with clindamycin-sensitive staphylococci, streptococci, bacteroidaceae, Fusobacterium necrophorum, Clostridium perfringens and osteomyelitis caused by Staphylococcus aureus. Clinacin tablets can also be used to help provide antimicrobial cover during dental procedures.

Dosage and administration

For oral administration.

1. For treatment of infected wounds, abscesses, oral cavity/dental infections, administer 5.5mg clindamycin per kg bodyweight twice daily for 7 - 10 days. Treatment may be extended to a maximum of 28 days based on clinical judgement. If no improvement is seen within 4 days, the sensitivity of the pathogens involved should be redetermined.

2. For the treatment of superficial pyoderma administer 11mg clindamycin per kg bodyweight once daily. Continue treatment for at least 21 days.

3. For the treatment of osteomyelitis administer 11 mg clindamycin per kg bodyweight twice daily for at least 28 days. If no improvement is seen within 14 days, the sensitivity of the pathogens involved should be redetermined.

4. To help provide antimicrobial cover during dental procedures, a 10 day course of 5.5 mg/kg every 12 hours is recommended (i.e. beginning 5 days before the intended procedure and continuing for 5 days thereafter).

Bodyweight

Infected wounds, abscesses, infected mouth cavity, dental infections

Superficial pyoderma

Osteomyelitis

5.5 mg/kg twice daily

11 mg/kg daily

11 mg/kg twice daily

4.5kg

1 x 25mg twice daily

2 x 25mg once daily

2 x 25mg twice daily

13.5kg

1 x 75mg twice daily

1 x 150mg once daily

1 x 150mg twice daily

27.0kg

1 x 150mg twice daily

1 x 300mg once daily

1 x 300mg twice daily

Contra-indications, warnings, etc

Do not administer to animals with hypersensitivity to clindamycin and lincomycin preparations. Do not administer to rabbits, guinea pigs, chinchillas, hamsters, horses or ruminants.

Before use of Clinacin tablets, the identification of causative pathogenic micro-organisms should be carried out and their susceptibility to clindamycin should be established.

Clindamycin and lincomycin show parallel-resistance. There is a partial cross-resistance to erythromycin and other macrolide-antibiotics.

Symptoms of overdose include vomiting, inappetency and diarrhoea. In such cases, treatment should be stopped immediately and the dogs treated symptomatically.

Clindamycin sometimes causes the overgrowth of non sensitive organisms such as resistant clostridia and yeasts. In cases of superinfection, appropriate measures should be taken according to the clinical situation.

Vomiting and diarrhoea are observed occasionally.

During prolonged therapy of one month or greater, periodic liver and kidney function tests and blood counts should be performed. Patients with severe renal and/or very severe hepatic disturbances accompanied by severe metabolic aberrations should be dosed with caution and should be monitored by serum examination during high dose clindamycin therapy.

While high dose studies in rats suggests that clindamycin is not a teratogen and does not significantly affect the breeding performance of males and females, safety in gestating bitches or breeding male dogs has not been established.

Neuromuscular blocking effects have been observed with clindamycin possibly leading to an increase of efficacy of other neuromuscular blocking agents. The concomitant use of such drugs must be handled with care.

General precautions

For animal treatment only.

Keep out of the reach of children.

Pharmaceutical precautions

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

This veterinary medicinal product does not require any special storage conditions.

Packaging Quantities

25mg - Polyethylene bottles containing 100 tablets.

75mg - polyethylene bottles containing 10, 16, 20, 30, 50, 80 and 100 tablets.

150mg - polyethylene bottles containing 10, 16, 20, 30, 50, 80 and 100 tablets.

300mg - white HDPE bottle containing: 6, 10, 14, 16, 20, 28, 30, 42, 50, 56, 60, 70, 80, 84, 98, 100 and 200 tablets

or

300mg - Alu/Alu Blister containing: 6, 10, 14, 20, 28, 30, 42, 50, 56, 60, 70, 84, 98, 100, 140, 180, 200, 250, 280, 300, 500 and 1000 tablets

Not all pack sizes may be marketed.

Legal category

POM-V

Further information

Clindamycin is an antibiotic with bacteriostatic action. Bactericidal actions have also been reported. Clindamycin is rapidly absorbed from the gastro-intestinal tract.

Marketing authorisation number

25mg - Vm 11990/4025.

75mg - Vm 11990/4018.

150mg - Vm 11990/4026.

300mg - Vm 11990/4053.

Need help or advice? Contact us:

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  • Email: support@viovet.co.uk

All prices include VAT where applicable.

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