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Below is the product datasheet. This has been provided by the manufacturer and should always be provided with the medication.
Introduction 
Company name: MSD Animal Health
Address: Walton Manor
Walton
Milton Keynes
MK7 7AJ
Telephone: 01908 685685 (Customer Support Centre)
Fax: 01908 685555
Email: vet-support.uk@merck.com
Website: www.msd-animal-health.co.uk
Presentation
A ready to administer, light yellow coloured, oral anthelmintic paste for horses and other equines. Each 28.5g syringe contains 11.4g pyrantel embonate as active ingredient.
Uses
A broad spectrum anthelmintic for the treatment of adult infections of large and small redworms, Ascarids and Pinworms found in the gastro-intestinal tract of horses, ponies and foals. Pyratape P also treats and controls tapeworm infection.
The broad spectrum activity includes:
Large roundworms - Parascaris equorum
Large strongyles - Strongylus vulgaris, S. edentatus, S. equinus
Small strongyles - Trichonema spp. (Cyathostomes), Triodontophorus spp.
Pinworms - Oxyuris equi, Probstmayria vivipara
Tapeworms - Anoplocephala perfoliata
Dosage and administration
Administer orally, one syringe per 600kg bodyweight as a single dose (=19mg pyrantel embonate per kg bodyweight).
Control and treatment of Strongyles, Oxyuris and Parascaris:
Pyratape P should be used at a dose rate of 19 mg pyrantel embonate per kg bodyweight. The dosing programmes are as follows:
-Foals (1-8 months of age): dose every 4 weeks.
-Horses (over 8 months of age): dose every 6-8 weeks, but during the summer and autumn when at grass dose every 4-6 weeks. Always dose 3-4 days before turning out after in wintering.
-Suckler mares: It has been shown that reduction of strongyle challenge to the suckling foal at pasture can be achieved by using clean pasture (re-seeded or not grazed the previous year by horses), dosing the mare 3-4 days before turning out and then at intervals of 2-4 weeks until the end of Autumn. Ideally mares with foals should go out to ‘clean’ pasture or, if this is not possible, delay turning them out until June.
The prescribed amount of Pyratape P is deposited on the tongue of the animal and the animal allowed to swallow. The complete content of one syringe contains 11.4g pyrantel embonate (6 graduated doses of 1.9g) in 28.5g paste and is sufficient for the treatment of 600kg bodyweight. Each graduation of the syringe is sufficient for the treatment of 100kg body-weight.
Control and treatment of Anoplocephala (Tapeworm):
Pyratape P should be used at a dose rate of 38mg pyrantel embonate per kg bodyweight (i.e. twice the dose used for strongyles). The need for re-treatment may vary, but if considered necessary, should be carried out after an interval of 6 weeks.
To ensure administration of a correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked.
Contra-indications, warnings, etc
Not for use in foals less than 4 weeks of age.
Do not use in animals with known sensitivity to pyrantel and in severely debilitated animals.
The same syringe should only be used to dose two animals if they are both healthy and are either running together, or are on the same premises and in direct contact with each other.
Pyrantel embonate is safe for horses and ponies of all ages, including sucklings, pregnant mares and studs. Impaction of the small intestine may occur in foals, infected with high numbers of Parascaris equorum. Symptoms (colic) may be seen as soon as 30 minutes after treatment. Combined administration of pyrantel and levamisole or piperazine is not recommended.
It is safe to give the product to pregnant and lactating mares provided the recommendations are followed.
General warnings: Care should be taken to avoid the following practices because they increase the risk of development of resistence and could ultimately result in ineffective therapy:
-Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
-Underdosing, which may be due to underestimation of weight, misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Resistance to pyrantel has been reported in cyathostomes in horses (also widespread in the USA and Canada). Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistence to anthelmintics.
Operator warnings: Direct contact with the skin should be avoided. Wash hands and any other parts of the body which comes into contact with the product after use. Avoid handling the product if you know you are hypersensitive to pyrantel.
Withdrawal periods:
Not to be used in horses and ponies intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse must have been declared as not intended for human consumption under national horse passport legislation.
For animal treatment only. Keep out of reach and sight of children.
Pharmaceutical precautions
Do not store above 25°C. Protect from direct sunlight. Keep syringe in outer carton.
Disposal advice:
Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.
Legal category
POM-VPS
Packaging Quantities
White, low density polyethylene syringe with a low density polyethylene cap. The syringe is fitted with a screw ring on a graduated plunger allowing adjustment of 1 to 6 doses of the product. Graduations on syringe at 100 kg bodyweight intervals.
Further information
Nil
Marketing authorisation number
Vm 12597/4013.
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