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Droncit for Dogs & Cats

Droncit for Dogs & Cats

Droncit contains the active drug Praziquantel and is one of the most safe and effective treatments for canine and feline tapeworms. Any dog that scavenges when out walking can easily become infected with tapeworms. Cats are also at risk, becoming infected from hunting and eating similarly infected prey - mice and birds are highly susceptible to worms, so consuming them can be hazardous. Both cats and dogs can also pick up a specific type of tapeworm from swallowing fleas when they groom themselves. A single dose of Droncit is all that is required to eradicate any tapeworms present in the gut. Licensed for use in dogs and cats.

Droncit Spot-On is a convenient, easy to administer treatment for tapeworms, probably the most common worms affecting cats. Droncit Spot-On can be used alongside flea preparations, although it is not advised that both be applied on the same day. Droncit contains the active ingredient Praziquantel, which is the same ingredient found in many expensive prescription worm treatments. For most cats, one application every 3 months would be advised.

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  • Spot-On for Cats » 20mg (Pack of 4 Pipettes)
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Description

Droncit Tablets 50mg Datasheet

Introduction

vet004
Company name: Bayer plc
Address: Animal Health Division
Bayer House, Strawberry Hill,
Newbury
Berkshire RG14 1JA
Telephone: 01635 563000
Fax: 01635 563622
Email: animal.health@bayer.com
Website: www.bayer.co.uk/animalhealth

Presentation

A white tablet containing 50 mg praziquantel.

Uses

For the treatment of adult tapeworms in dogs and cats. The tablets are effective against both immature and mature forms of adult tapeworms in both dogs and cats.
he product is a highly effective treatment against all the common species of tapeworm infecting dogs and cats in the United Kingdom and Ireland including Echinococcus granulosus, Taenia ovis, Taenia pisiformis, Taenia multiceps, Taenia hydatigena, Taenia taeniaeformis, and Dipylidium caninum. Droncit is also effective against Echinococcus multilocularis (As a precautionary measure to prevent the establishment of Echinococcus multilocularis in the UK and Ireland, it is recommended that all dogs and cats entering the country be treated with praziquantel.

Dosage and administration

The recommended dosage rate is 5 mg/kg body weight. This corresponds to 1 tablet per 10 kg body weight.

Dogs: Body weight
2.55.0 kg tablet
6.010.0 kg 1 tablet
11.020.0 kg 2 tablets
21.030.0 kg 3 tablets
Over 30 kg pro rata
Cats:
Adult cats tablet

Oral administration.
The tablets are administered by opening the animal's mouth and pushing the tablet over the back of the tongue so that it cannot be rejected. Alternatively, a tablet can be wrapped in a piece of meat or butter and offered to the animal or crushed and mixed with the food.
A single dose is all that is required. However, for dogs in rural areas and for packs of hounds this dose should be repeated every four weeks to ensure that newly acquired tapeworms are destroyed before reaching maturity. Dosing must be associated with strict control of the dog's diet to ensure that uncooked offal is not eaten.
Use during pregnancy and lactation
The product may be administered to pregnant females. It is safe to the female herself, to the unborn foetus and to the newborn young.

Contra-indications, warnings, etc

Do not administer to dogs weighing less than 2.5 kg.
Do not administer to unweaned puppies and kittens, as such animals are rarely infected with tapeworms.
Fleas serve as intermediate hosts for one common type of tapeworm - Dipylidium caninum. To avoid reinfection with this parasite, flea control of the animal and its housing should be carried out at the same time. Unless flea control is complete an infected flea population may survive: i.e. re-treatment of the animal may be necessary.
As a precautionary measure to prevent the establishment of Echinococcus multilocularis in the UK and Ireland, it is recommended that all dogs and cats entering the country be treated with praziquantel.
Any part used tablets should be discarded.
User safety
In the interests of good hygiene, persons administering the tablets directly to the animal, or by adding them to the animal's food, should wash their hands afterwards.
Environmental safety
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

Pharmaceutical precautions

Do not store above 25C. Store in a dry place.
Shelf-life of the veterinary medicinal product as packaged for sale: 5 years

Legal category

AVM-GSL

Packaging Quantities

Cartons containing laminated aluminium foil /polyethylene blister pack with either 2 x 10 or 10 x 10 tablet blisters.

Further information

Praziquantel is a pyrazino-isoquinolin derivative, with anthelmintic activity. ATC Vet Code: QP 52 AA 01. The spectrum of action of praziquantel covers all the important species of cestodes in dogs and cats. It specifically includes all Taenia species occurring in dogs and cats, Multiceps multiceps, Joyeuxiella pasquali, Dipylidium caninum, Mesocestoides species, Echinococcus multilocularis and E. granulosus. Praziquantel is effective against all stages of development of these parasites occurring in the intestines of dogs and cats. Praziquantel impairs the normal tegument function of the parasite, making it permeable to excessive glucose loss and thereby more easily attacked by proteolytic enzymes. Because of this, whole tapeworms including the scolex are very rarely passed in the faeces following administration of the drug. Disintegrated and partially digested fragments may occasionally be seen in the faeces. Praziquantel is rapidly absorbed by the animal and metabolised by the liver. It is excreted, entirely as metabolites, in the urine and faeces.

Marketing authorisation number

Vm 00010/4097

Droncit Spot-On 20mg Solution Datasheet

Introduction

vet004
Company name: Bayer plc
Address: Animal Health Division
Bayer House, Strawberry Hill,
Newbury
Berkshire RG14 1JA
Telephone: 01635 563000
Fax: 01635 563622
Email: animal.health@bayer.com
Website: www.bayer.co.uk/­animalhealth

Presentation

A clear, colourless to slightly reddish, spot-on solution containing 20 mg praziquantel per 0.5 ml tube with butylated hydroxytoluene.

Uses

For the treatment of tapeworms of cats. The product is effective against mature and immature forms of Dipylidium caninum and Taenia species. The product is also effective against Echinococcus multilocularis.

Dosage and administration

The minimum dose rate is 8 mg/kg bodyweight, which equates to 1 tube per 2.5 kg bodyweight.

Bodyweight (kg) Number of
tubes
Quantity of
Praziquantel (mg)
mg/kg
Bodyweight
1-2.5 1 20 8-20
>2.5-5 2 40 8-16
>5 3 60 maximum 12

Method of administration
Remove one tube from the package. Hold the tube in an upright position, twist and pull off cap. Use reversed cap to twist and remove seal from tube. See figure 1.


Advantix - Opening pipette (1)
Figure 1: Opening a tube

Part the hair on the cat’s neck at the base of the skull until the skin is visible. See figure 2.

Application to cat
Figure 2: Administration

Place the tip of the pipette on the skin and squeeze firmly several times to empty the contents directly onto the skin. Application at the base of the skull will minimise the opportunity for the cat to lick the product.
To minimise the possibility of run-off after application of more than one pipette, it is advised that the applications should be performed slowly to allow absorption and that it may be advisable to allow the contents of the previous pipette to be absorbed before applying another.
Tapeworm infection is certain to re-occur unless control of the intermediate hosts such as fleas, mice, etc, is undertaken.
Flea control
Flea infestations can be controlled by the regular use of effective flea control remedies.
Mice control
If cats roam and hunt, contact with, and consumption of, mice and subsequent re-infestation with Taenia taeniaeformis is impossible to prevent.
It is recommended to re-apply Droncit Spot-On when signs of tapeworm infection re-appear or at monthly intervals.
Use During Pregnancy and Lactation
There are no contra-indications against use during pregnancy and lactation.

Contra-indications, warnings, etc

Do not use on cats weighing less than 1 kg bodyweight.
Do not allow recently treated animals to groom each other. Care should be taken to avoid the contents of the tube coming into contact with the eyes or mouth of the recipient animal. For external use only.
Occasionally a transient local reaction such as scurf or mild exudation may be observed at the application site following treatment.
The product is bitter tasting and salivation may occasionally occur if the cat licks the application site immediately after treatment. This is not a sign of intoxication and disappears after a short time without treatment.
No incompatibility has been observed between this product at the recommended dose and a range of common veterinary treatments.
Overdosing can lead to slight skin reactions which disappear without treatment within a few days.
Withdrawal period(s)
Not applicable as the product is not indicated for the treatment of food producing animals.
User safety
This product can be irritant to the skin and eyes.
Care should be taken to prevent contact of the solution with the skin or eyes. If contact with the skin occurs, wash off any skin contamination with soap and water immediately.
If accidental contact occurs with the eyes, flush the affected eyes thoroughly with clean fresh water.
In the event of skin or eye contact, seek medical advice if irritation persists and show the Doctor this package.
Do not stroke or groom animals until area of application is dry (typically around 1 hour after application).
Wash hands thoroughly after use. Do not eat, drink or smoke during application.
Store away from food, drink or animal feedingstuffs.
Environmental safety
Any unused product or waste material should be disposed of in accordance with national requirements.

Pharmaceutical precautions

Store away from food, drink and animal feeding stuffs. Do not use after expiry date.
Shelf-life of the product as packaged for sale: 5 years
Shelf-life after dilution or reconstitution: Not applicable, the product is presented in a ready-to-use solution.
Shelf-life after first opening the container: Not applicable, once opened, the entire contents of the tube is applied to the animal's skin.

Legal category

AVM-GSL

Packaging Quantities

Blister pack, containing 4 unit dose polypropylene tubes with white polypropylene caps , each containing 0.5 ml solution per tube (20 mg praziquantel).

Further information

The Active Ingredient
Praziquantel, the active ingredient of Droncit® Spot-on is a pyrazinoisoquinoline derivative used widely as an anthelmintic for both human and veterinary medicine. The chemical name for this substance is 2-cyclohexyl-carbonyl[1,2,3,6,7,11b] hexahydro-4H-pyrazino-[2,1-a]isoquinolin-4-one[1]. ATCVet Code: QP52AA01.
Praziquantel is effective against all stages of development of intestinal tapeworms. The substance is very rapidly absorbed and distributed throughout the parasite. Both in vivo and in vitro studies have shown that praziquantel causes severe damage to the parasite integument, resulting in contraction and paralysis. There is an almost instantaneous tetanic contraction of the parasite musculature and a rapid vacuolisation of the syncytial tegument. This rapid contraction has been explained by changes in divalent cation fluxes, particularly calcium.
Praziquantel is absorbed very rapidly and almost completely in the stomach and small intestine. Studies of the behaviour following oral administration have been conduced in rats, dogs, monkeys, sheep and humans. Depending on species, maximum serum levels are reached within 0.3 to 2 hours. The chemical is evenly distributed to all organs. The elimination half-lives of 14C-praziquantel and its metabolites are between 2 and 3 hours in rats, dogs, monkeys and sheep.
Praziquantel is rapidly metabolised in the liver in both humans and animals with the 4-hydroxycyclohexyl derivative as the main metabolite. Praziquantel is completely eliminated from the body within 48 hours; irreversible binding to body constituents has not been observed. Elimination is in the form of metabolites with virtually no parent compound excreted. Between 40% and 71% of the substance is eliminated in the urine and 13%-30% in the faeces.

Marketing authorisation number

Vm 00010/4105

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  • Freephone: 0800 084 2608
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Reviews of Droncit for Dogs & Cats

Read our customers' reviews of Droncit for Dogs & Cats

Questions & Answers for Droncit for Dogs & Cats

Below are some recent questions we've received regarding Droncit for Dogs & Cats, including answers from our team.

Ask Your Own Question

Use on pregnant cat

19th Feb 2014
sharon

Can this spot on wormer be used for pregnant cat?

Danielle Fletcher
  • AMTRA Qualified Product Advisor at VioVet

Yes, this wormer can be used on a pregnant cat. There are no contra-indications against using Droncit Spot On during pregnancy and lactation.

Can I use this with Advocate to treat tapeworms?

16th Dec 2013
Sara Bullard

I am in the process of ordering Advocate for my 18 month old lab which she has had since a pup, but I never realised she wasn't covered for tapeworm. Whilst looking for tapeworm tablets on your site it says not to feed your dog offal. Does this mean just on the day the tablets are given? Also it is not quite clear how often the medication must be used, please can you advise?

John Cousins
  • Veterinary Surgeon at VioVet

There is not a simple answer to this question. Most dogs these days probably never come across a tapeworm, so do not need routine, regular treatment. If they do get a tapeworm, then usually you become aware of it, unlike other worms which normally remain completely hidden. (Tapeworm segments wriggle out of a dogs bottom and are seen crawling through the hair near the bottom. They are whitish in colour and look a bit like a large, flattened grain of rice.) Tapeworms are usually seen in dogs which scavenge rabbit carcases when out on walks, or in dogs fed on raw offal, hence the advice you have seen. Dogs can also pick up tapeworms from eating fleas or lice when grooming themselves, but this type of tapeworm is much less common now that flea treatments are so much more effective.

Any particular dose of tapeworm treatment will kill any tapes present at the time of dosing, but will have no on-going protective effect. Tapeworms are regarded as unpleasant but not dangerous, so it is not really a disaster if a dog does pick one up, though they do appear rather objectionable!

Personally I would probably just continue with Advocate (for fleas and other worms) and not bother with tapeworm treatment unless your dog is in a high risk group (eats potentially infected foods regularly). Some people will give a tapeworm dose once per year, or even once every 3 months as a precaution, and that is not wrong, but is usually not required. Droncit tablets are the usual choice where this is done. You can decide yourself if your dog warrants regular, precautionary treatment for tapeworms, or ask your vets what they think.

Frequency of worming a dog

10th Sep 2013
Lesley Adam

Please can you tell me how often I should give my dog a worming tablet ?

  • Product Management Team at VioVet

You should give your dog 1 tablet per 10kg body weight. If your dog weighs 5kg then you should give him half a tablet. If your dog weighs 6 - 10kg then you should give him 1 tablet, 11 - 20kg = 2 tablets, 21 - 30kg = 3 tablets etc. The dosage only needs to be given once, however, dogs in rural areas or packs of hounds the dose should be repeated every 4 weeks.

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