Therios Palatable Tablets | 
Therios are flavoured antibiotic tablets which can be given directly or in food. They contain the well known antibiotic cefalexin, which is safe and effective for many types of infection in dogs and cats. Therios is particularly used for skin infections (superficial and deep pyoderma) and urinary infections. It can also be used to treat infected wounds, and a wide range of other soft tissue infections. Therios is usually dosed twice daily. The dose rate and length of treatment course vary depending on the nature of the infection to be treated. For the full datasheet, click on the product names below.
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|  | Customers who purchased these items also purchased |   | | Below is the product datasheet. This has been provided by the manufacturer and should always be provided with the medication. Introduction 
Company name: Alstoe Ltd
Address: The Industrial Park
Sheriff Hutton
York
YO60 6RZ
Telephone: 01347 878606
Fax: 01347 878333
Email: info@alstoe.co.uk
Website: www.alstoe.co.uk
Presentation
Oblong scored beige chewable tablet. Each tablet contains: Cefalexin (as cefalexin monohydrate) 75 mg. The tablet can be divided into equal halves
Uses
Cats: For the treatment of infections caused by bacteria susceptible to cefalexin.
Lower urinary tract infections due to E.coli and Proteus mirabilis.
Treatment of cutaneous and subcutaneous infections: pyoderma due to Staphylococcus spp. and wounds and abscesses due to Pasteurella spp.
Dosage and administration
15 mg cefalexin per kg bodyweight orally twice daily, equivalent to 1 tablet for 5 kg bodyweight for:
- 10-14 days in case of urinary tract infection
- 5 days for wounds and abscesses
- 14 days at least in case of pyoderma. The treatment must be continued for 10 days once the lesions have disappeared.
To ensure a correct dosage body weight should be determined as accurately as possible to avoid under dosing.
The tablets are flavoured. They can be administered with food or directly into the mouth of the animal.
Contra-indications, warnings, etc
Do not use in animals which are known to be hypersensitive to cephalosporins or any other substance from the β-lactam group.
The product is contra-indicated in case of a known resistance to cefalexin.
Do not use in rabbits, guinea pigs, hamsters, gerbils and other small rodents.
Do not use in case of severe kidney failure
As with other antibiotics which are excreted mainly by the kidneys, unnecessary accumulation may occur in the body when renal function is impaired. In cases of known renal insufficiency the dose should be reduced and/or the interval of administration increased and nephrotoxic drugs should not be administered concurrently.
The product should not be used to treat kittens less than 9 weeks of age.
The use of the product in cats weighing less than 2.5 kg should be in accordance with the benefit/risk assessment performed by the responsible veterinarian.
The safety of the products has not been investigated in pregnant or lactating cats and should only be used according to the benefit/risk assessment by the responsible veterinarian.
Vomiting and/or diarrhoea have been observed in cats. In case of recurring vomiting and/or diarrhoea, the treatment should be discontinued and the advice of the attending veterinarian sought.
The bactericidal activity of cephalosporins is reduced by concomitant administration of bacteriostatic acting compounds (macrolides, sulfonamides and tetracyclines). Nephrotoxicity can be increased when 1st generation cephalosporins are combined with polypeptide antibiotics, aminoglycosides or some diuretics (furosemide). Concomitant use with such active substances should be avoided.
Pharmaceutical precautions
Do not store above 25 °C. Keep out of the reach of children.
Half tablets should be stored back in the blister pocket and used for the next administration. Any divided tablet portion remaining after 24 hours should be discarded.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Legal category
POM-V
Packaging Quantities
Carton containing 20 blisters of 10 tablets
Further information
Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Cephalosporins may cause sensitization (allergy) following injection, inhalation, ingestion or skin contact. Sensitivity to penicillins may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious.
1. Do not handle this product if you know you are sensitized or if you have been advised not to work with such preparations.
2. Handle this product with great care to avoid exposure, taking all recommended precautions. Wash hands after use.
3. If you develop symptoms following exposure such as skin rash you should seek medical advice and show the doctor this warning. Swellings of the face, lips or eyes or difficulty breathing are more serious symptoms and require urgent medical attention.
4. In case of accidental ingestion, seek medical attention and show the package leaflet or the label to the doctor.
Wherever possible, the use of the product should be based on susceptibility testing.
Official and local antimicrobial policies on antibiotherapy should be taken into account when the product is used.
Use of the product deviating from the instructions given may increase the prevalence of bacteria resistant to the cefalexin and may decrease the effectiveness of treatment with penicillins due to the potential for cross resistance.
Marketing authorisation number
Vm 20749/4019.
Below is the product datasheet. This has been provided by the manufacturer and should always be provided with the medication. Introduction
Company name: Alstoe Ltd
Address: The Industrial Park
Sheriff Hutton
York
YO60 6RZ
Telephone: 01347 878606
Fax: 01347 878333
Email: info@alstoe.co.uk
Website: www.alstoe.co.uk
Presentation
Round scored beige palatable tablet. Each tablet contains: Cefalexin (as cefalexin monohydrate) 300 mg. The tablet can be divided into equal halves and quarters
Uses
Dogs: For the treatment of bacterial skin infections (including deep and superficial pyoderma) caused by organisms sensitive to cefalexin.
For the treatment of urinary tract infections (including nephritis and cystitis) caused by organisms sensitive to cefalexin.
Dosage and administration
15 mg cefalexin per kg bodyweight twice daily (equivalent to 30 mg per kg bodyweight per day) for duration of:
- 14 days in cases of urinary tract infection
- At least 15 days in cases of superficial infectious dermatitis
- At least 28 days in cases of deep infectious dermatitis
In severe or acute conditions the dose may be safely doubled to 30 mg/kg twice daily.
Therios tablets are well accepted by dogs, but may be crushed or added to a small quantity of food immediately prior to feeding if necessary.
Contra-indications, warnings, etc
Do not use in animals which are known to be hypersensitive to penicillins.
Do not use in rabbits, guinea pigs, hamsters and gerbils.
Do not use in pregnant or lactating bitches.
As with other antibiotics which are excreted mainly by the kidneys, systemic accumulation may occur when renal function is impaired. In case of known renal insufficiency the dose should be reduced.
The product is not recommended for use in dogs less than 2.5 kg bodyweight.
Safety of the excipient, ammonium glycyrrhizate, has not been established in dogs less than 1 year old.
Pharmaceutical precautions
Do not store above 25 °C. Keep out of the reach of children.
Shelf-life after first opening the blister pack: 48 hours.
Divided tablets should be stored in the blister pack. Any divided tablet portions remaining after 48 hours should be discarded.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Legal category
POM-V
Packaging Quantities
Carton containing 20 blisters of 10 tablets
Further information
Trials performed on animals with up to 5 times the recommended dosage 15 mg/kg demonstrated that cefalexin was well tolerated.
Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Cephalosporins may cause sensitization (allergy) following injection, inhalation, ingestion or skin contact. Sensitivity to penicillins may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious.
1. Do not handle this product if you know you are sensitized or if you have been advised not to work with such preparations.
2. Handle this product with great care to avoid exposure, taking all recommended precautions. Wash hands after use.
3. If you develop symptoms following exposure such as skin rash you should seek medical advice and show the doctor this warning. Swellings of the face, lips or eyes or difficulty breathing are more serious symptoms and require urgent medical attention.
Marketing authorisation number
Vm 20749/4004.
Below is the product datasheet. This has been provided by the manufacturer and should always be provided with the medication. Introduction
Company name: Alstoe Ltd
Address: The Industrial Park
Sheriff Hutton
York
YO60 6RZ
Telephone: 01347 878606
Fax: 01347 878333
Email: info@alstoe.co.uk
Website: www.alstoe.co.uk
Presentation
Round scored beige palatable tablet. Each tablet contains: Cefalexin (as cefalexin monohydrate) 750 mg. The tablet can be divided into equal halves and quarters
Uses
Dogs: For the treatment of bacterial skin infections (including deep and superficial pyoderma) caused by organisms sensitive to cefalexin.
For the treatment of urinary tract infections (including nephritis and cystitis) caused by organisms sensitive to cefalexin.
Dosage and administration
15 mg cefalexin per kg bodyweight twice daily (equivalent to 30 mg per kg bodyweight per day) for duration of:
- 14 days in cases of urinary tract infection
- At least 15 days in cases of superficial infectious dermatitis
- At least 28 days in cases of deep infectious dermatitis
In severe or acute conditions the dose may be safely doubled to 30 mg/kg twice daily.
Therios tablets are well accepted by dogs, but may be crushed or added to a small quantity of food immediately prior to feeding if necessary.
Contra-indications, warnings, etc
Do not use in animals which are known to be hypersensitive to penicillins.
Do not use in rabbits, guinea pigs, hamsters and gerbils.
Do not use in pregnant or lactating bitches.
As with other antibiotics which are excreted mainly by the kidneys, systemic accumulation may occur when renal function is impaired. In case of known renal insufficiency the dose should be reduced.
The product is not recommended for use in dogs less than 2.5 kg bodyweight.
Safety of the excipient, ammonium glycyrrhizate, has not been established in dogs less than 1 year old.
Pharmaceutical precautions
Do not store above 25 °C. Keep out of the reach of children.
Shelf-life after first opening the blister pack: 48 hours.
Divided tablets should be stored in the blister pack. Any divided tablet portions remaining after 48 hours should be discarded.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Legal category
POM-V
Packaging Quantities
Carton containing 20 blisters of 10 tablets
Further information
Trials performed on animals with up to 5 times the recommended dosage 15 mg/kg demonstrated that cefalexin was well tolerated.
Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Cephalosporins may cause sensitization (allergy) following injection, inhalation, ingestion or skin contact. Sensitivity to penicillins may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious.
1. Do not handle this product if you know you are sensitized or if you have been advised not to work with such preparations.
2. Handle this product with great care to avoid exposure, taking all recommended precautions. Wash hands after use.
3. If you develop symptoms following exposure such as skin rash you should seek medical advice and show the doctor this warning. Swellings of the face, lips or eyes or difficulty breathing are more serious symptoms and require urgent medical attention.
Marketing authorisation number
Vm 20749/4013.
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