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Off-white, sugar-coated, unscored, circular antibacterial tablets. Each tablet contains: Trimethoprim Ph.Eur 20 mg Sulphadiazine Ph.Eur 100 mg.
Uses
Norodine 20 Tablets are indicated for oral use in dogs and adult cats. Together the active ingredients produce a double blockade of folinic acid synthesis in bacteria resulting in a level of activity much greater than that obtained from either drug alone. In vitro Norodine is effective against most common Gram-positive and Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, Pasteurella spp., Streptococcus spp., Staphylococcus spp., Salmonella spp., Corynebacterium spp., Proteus mirabilis and Citrobacter freundii. When susceptible organisms are present Norodine 20 Tablets may be effective in treating the following conditions: alimentary tract infections; respiratory and urogenital infections; skin and wound infections; eye and ear infections.
Dosage and Administration
This product should be administered orally by hand. The daily dose is 30 mg of combined active ingredients per kg bodyweight. This is achieved using the following doses: Dogs and Adult Cats: One tablet per 4 kg bodyweight daily. Maintain adequate fluid intake during treatment. Treatment should be continued for up to five days or until two days after symptoms have subsided.
Contra Indications When given to cats the tablets should not be divided or crushed before administration. A low incidence of polyarthropathy and Keratoconjunctivitis Sicca (Dry Eye) has been reported in dogs following oral administration of potentiated sulphonamides. If either of these conditions occur, it is recommended that medication is stopped and that future treatment with similar products is avoided. Wash hands after use.  White, circular, uncoated antibacterial tablets scored on one side. Each tablet contains: Trimethoprim Ph.Eur 80 mg Sulphadiazine Ph.Eur 400 mg.
Uses
Norodine 80 Tablets are indicated for oral use in dogs. Together the active ingredients produce a double blockade of folinic acid synthesis in bacteria, resulting in a level of activity much greater than that obtained from either drug alone. In vitro Norodine is effective against most common Gram-positive and Gram-negative bacteria including Escherichia coli, Klebsiella pneumoniae, Pasteurella multocida, Streptococcus spp., Staphylococcus spp., Salmonella spp., Corynebacterium spp., Proteus mirabilis and Citrobacter freundii. When susceptible organisms are present Norodine 80 Tablets may be effective in treating the following conditions: alimentary tract infections; respiratory and urogenital infections; skin and wound infections; eye and ear infections.
Dosage and Administration
This product should be administered orally by hand. Dogs: The daily dose is one tablet per 16 kg bodyweight given orally, providing 30 mg of combined active ingredients per kg bodyweight. Treatment should be continued for up to five days or until two days after symptoms have subsided.
Contra Indications
This dosage form is not suitable for use in cats. Norodine 20 Tablets should be administered to this species. A low incidence of polyarthropathy and Keratoconjunctivitis Sicca (Dry Eye) has been reported in dogs following oral administration of potentiated sulphonamides. If either of these conditions occur, it is recommended that medication is stopped and that future treatment with similar products is avoided. Not recommended in cases with hepatic dysfunction. Sulphonamide sensitivity is rare in companion animals but should be considered in cases of unexpected responses to treatment. Wash hands after use. 
 Each syringe contains 45 g of oral paste containing:
Uses
For the treatment of bacterial infections in horses.
Dosage and Administration
The daily dose is 30 mg combined active ingredients per kg bodyweight. Each syringe provides one daily dose for a 500kg horse. Each division on the dial-a-dose plunger provides sufficient product to treat 50kg of bodyweight. Treatment should be continued for up to five days or until two days after symptoms have resolved. Drug absorption may be greater if food is withheld for a few hours prior to dosing.
Administration: Adjust screw gauge on dial-a-dose plunger to the bodyweight of the horse. Remove cap from nozzle. Place nozzle in corner of mouth. Depress plunger depositing paste on upper surface of tongue. Replace cap after use.
Contra Indications Do not use in horses intended for human consumption. Do not use in cases of known hypersensitivity, severe hepatic dysfunction or cardiac arrhythmias. Do not use the same syringe to treat more than one animal unless horses are running together or in direct contact with each other on the same premises. This product is known to cause allergic reactions in sensitive individuals, do not use this product if you have a known allergy to this or similar products. Take care to avoid skin contact. In case of skin contact wash affected area thoroughly. If irritation occurs/persists seek medical advice. Take care to avoid accidental eye contact by wearing suitable eye protection. In the case of accidental eye contact flush thoroughly with clean water and seek medical advice.  White
to off-white granules with broad-spectrum antibacterial activity.
Presented in aluminium foil sachets. Norodine Granules are for oral
administration to horses after mixing with feed. Each sachet contains
37.5 g of product containing:
Uses
For the treatment of bacterial infections in horses.
Dosage and Administration
Dosage:
The daily dose is 30 mg combined active ingredients per kg bodyweight (25 mg sulfadiazine and 5 mg trimethoprim per kg bodyweight). Each sachet contains one daily dose for a 500 kg horse.
Treatment should be continued for up to 5 days or until 2 days after symptoms have resolved.
The scoop provided dispenses 15g of granules.
Administration:
After careful estimation of the weight of the horse, the required dose of Norodine Granules should be mixed well with the horse's feed prior to administration.
Contra Indications Do not use in horses intended for human consumption. Do not use in horses with known sulphonamide sensitivity, with hepatic damage or with blood dyscrasias. Avoid inhalation and direct contact with skin. Wash hands after use.  A clear yellow aqueous solution for parenteral administration containing as active ingredients per ml Sulphadiazine BP 200 mg and Trimethoprim BP 40 mg. Preservative: Chlorocresol 1 mg/ml.
Uses
Norodine 24 is indicated in the treatment of acute, subacute and chronic conditions of bacterial origin in horses, cattle, sheep, pigs, dogs and cats. The therapeutic spectrum includes both Gram-negative and Gram-positive bacteria including Streptococci, Staphylococci, Actinobacilli, Actinomycae, Salmonella, Pasteurella, Pneumococci, Proteus, E. coli, Corynebacteria, Vibrio, Bordetella, Brucella, Klebsiellae and Haemophilae. It is also indicated in species where there may be an existing antibiotic drug resistance. Norodine 24 may be administered in respiratory infections of bacterial origin including rhinitis, pneumonia, bronchitis and in bacterial infections secondary to viral disease such as viral pneumonia or mycoplasma infections. It is also indicated in urogenital tract infections (cystitis, vaginitis, urethritis, nephritis and metritis) and alimentary tract infections (including neonatal diarrhoea and salmonellosis). Other infections include foul-in-the-foot, severe mastitis, bacterial agalactia of sows, and infections of eye, ear and mouth.
Dosage and Administration
For cattle, sheep and pigs the dose is 1 ml per 16 kg bodyweight daily by intramuscular or slow intravenous injection. Norodine 24 may be administered by intravenous injection when rapid blood levels of sulphadiazine and trimethoprim are required. For horses the dose is 1 ml per 16 kg bodyweight by slow intravenous injection. For dogs and cats 1 ml per 8 kg bodyweight, by subcutaneous injection only. The recommended site in dogs is the loose skin at the top of the neck. A single injection may be sufficient in uncomplicated conditions, but in severe infections it may be repeated for up to 5 days, or until 2 days after the symptoms resolve. An appropriately graduated syringe must be used to allow accurate administration of the required dose volume. This is particularly important when injecting small volumes.
Contra Indications Injections should not be given by routes other than those recommended. Not to be administered intraperitoneally. Norodine 24 is contra-indicated in animals with known sulphonamide sensitivity, severe liver parenchymal damage, or blood dyscrasias. Milk for human consumption must not be taken from a cow during treatment. Milk for human consumption may only be taken after 48 hours from the last treatment. Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after 12 days from the last treatment. Pigs may be slaughtered for human consumption only after 20 days from the last treatment. Adequate drinking water should be available during the therapeutic effect of the product. This product should not be used in horses intended for human consumption. Do not administer to horses exhibiting drug-induced cardiac arrhythmias. Such arrhythmias may be associated with the administration of certain anaesthetic and sedative agents. Anaphylactic shock, potentially fatal, has been observed on rare occasions following administration of potentiated sulphonamide preparations, particularly by the intravenous route. Veterinary surgeons should be mindful of this possibility during the injection process. For intravenous administration the product should be warmed to body temperature and injected slowly over as long a period as is reasonably practical. At the first sign of intolerance the injection should be interrupted and shock treatment initiated. Care must be taken to avoid accidental self-injection.  | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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